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hrp0089p2-p313 | Pituitary, Neuroendocrinology and Puberty P2 | ESPE2018

Neuroendocrine Consequences of Hypothalamic Hamartoma and their Imaging (MRI) and Surgery Correlates

Corredor Beatriz , Caredda Elisabetta , Ederies Ash , Tisdall Martin , Cross Helen , Spoudeas Helen A.

Background: Hypothalamic hamartomas(HH) are rare heterotopic congenital malformations causing central precocious puberty(CPP) and/or resistant epilepsy whose natural history is unknown.Aim: To describe clinical and imaging features, and the risk of developing endocrine deficits, particularly after surgery.Method: Retrospective case note and imaging review of all HH diagnosed by MRI between 30.08.1991 and 24.11.17, analysed by initi...

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hrp0084p3-1148 | Puberty | ESPE2015

Endocrine Dysfunction in Hypothalamic Hamartoma Depends on Presentation (Endocrine or Epileptogenic), Radiological Characteristics and Surgery

Caredda Elisabetta , Wilkinson Robert , Ederies Ash , Improda Nicola , Varadkar Sophia , Cross Helen , Tisdall Martin , Spoudeas Helen A

Background: Hypothalamic hamartomas(HH)-rare heterotopic congenital malformations (incidence 1:200 000)-present with central precocious puberty (CPP) or gelastic seizures (GS) but their natural history and best treatment strategy are unknown. Given their proximity to the hypothalamuspituitary axis, wider endocrine dysfunction may be expected.Objective and hypotheses: To describe clinical features and any evolving endocrinopathies in HH patients, by...

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ESPE Abstracts

Neuroendocrine Consequences of Hypothalamic Hamartoma and their Imaging (MRI) and Surgery Correlates

Endocrine Dysfunction in Hypothalamic Hamartoma Depends on Presentation (Endocrine or Epileptogenic), Radiological Characteristics and Surgery

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